Gardner-Diamond syndrome: psychogenicillness withimmuno-inflammatory component

Hanane ATARGUINE , MD, OuafaHOCAR,MD, PhD, Nadia AKHDARI ,MD, PhD, Said AMAL,MD, PhD Department of Dermatology, ArraziHospital , CHU MohamedVI, Marrakech. Faculty of Medicineand Pharmacy-Cadi AyyadUniversityMarrakech _ _______________________________________________________________________________ ABSTRACT Gardner-Diamond syndrome also known as auto erythrocyte sensitization syndrome is an extremely rare disorder characterized by the spontaneous appearance of painful bruises that may interest all parts of the body.We report a rare case of this syndrome in association with Sjögren syndrome in a 24-year-old woman , who had an angioedema during the follow-up. Although Gardner-Diamond syndrome is not classified as self-inflammatory, it has been described in association with certain auto immune or inflammatory diseases:systemic lupus erythematosus, immune complex nephrit is, hypocomplementaemia, idiopathic thrombocytopenic purpura, lymphadeno pathyangio-immuno plastique and the presence of anticardiolip in antibodies.The association of this syndrome with immunological and inflammatory abnormalities, assuggested in our case, requires further study.